Hi @frandicicco
This spec of PC is enough for using a POP.
If the Handy Scan crash immediately after you plug it to your PC, then you can check if the camera permission is allowed. Here is another post for your reference: [Tips] Remember to check the camera permission of your PC
Hope you can create a video with your connection method and show the problem, then we can lear more details about your problem.
Best Regards
Cassie